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13 mar 2023 · Cold urticaria is a chronic condition causing episodic symptoms of cold-induced wheals or angioedema in response to direct or indirect exposure to cold temperatures. Whereas symptoms of cold urticaria are typically benign and self-limiting, severe systemic anaphylactic reactions are possible.
MANAGEMENT OF COLD URTICARIA SYNDROMES. The decision to treat cold urticaria syndromes depends primarily on the underlying etiology, severity of response to cold stimulus, and how greatly it affects quality of life, including the frequency of anticipated cold exposure.
8 lis 2023 · Cold urticaria is characterized by pruritic wheals (hives) and/or angioedema due to cutaneous mast cell degranulation and their release of proinflammatory mediators after cold exposure of the skin. Triggers include skin contact with cold objects, cold liquids, and cold air.
Our systematic review included 16 studies, 9 of which met the eligibility criteria for the meta-analysis. We analyzed the effects of treatments on critical temperature thresholds (CTTs) and critical stimulation time thresholds (CSTTs), as well as on rates of complete response and adverse events.
Chronic urticaria (CU) is a common disease which represents a considerable burden for many patients. The current urticaria guideline describes the evidence-based diagnosis and treatment of CU. In addition, however, questions often arise in everyday practice that are not addressed by the guideline.
This updated version of the international guideline for urticaria covers the definition and classification of urticaria and outlines expert-guided and evidence-based diagnostic and therapeutic approaches for the different subtypes of urticaria.
Non-sedating H1-antihistamine is the first-line treatment for 2-4 weeks; if urticaria was not controlled, increasing the dose up to 4 times is recommended. Sedating first-generation antihistamines have not been proven more advantage than non-sedating antihistamines.