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13 mar 2023 · The decision to treat cold urticaria syndromes depends primarily on the underlying etiology, severity of response to cold stimulus, and how greatly it affects quality of life, including the frequency of anticipated cold exposure.
Our systematic review included 16 studies, 9 of which met the eligibility criteria for the meta-analysis. We analyzed the effects of treatments on critical temperature thresholds (CTTs) and critical stimulation time thresholds (CSTTs), as well as on rates of complete response and adverse events.
8 lis 2023 · Cold urticaria is characterized by pruritic wheals (hives) and/or angioedema due to cutaneous mast cell degranulation and their release of proinflammatory mediators after cold exposure of the skin. Triggers include skin contact with cold objects, cold liquids, and cold air.
11 lip 2021 · In cold urticaria, skin exposure to cold is the relevant trigger. Patients with cold urticaria show itchy wheal and flare type skin reactions or angioedema at exposed skin sites, typically within minutes after cold contact (cold air, cold liquids or objects).
Cold urticaria is a hypersensitivity to cold exposure (eg, wind, freezer compartments, cold water) resulting in histamine release. It usually presents as localized redness, burning, pruritus, and urticaria in the exposed areas, but may progress to a generalized systemic reaction, shock, and death.
PMID: 26919357. Abstract. Cold urticaria is a physical urticaria characterized by a localized or systemic eruption of papules upon exposure of the skin to cold air, liquids, and/or objects. In some cases, angioedema and anaphylaxis also may occur. The symptoms of cold urticaria can have a negative impact on patients' quality of life.
1 mar 2022 · Issue Section: Guidelines > Evidence‐Based Dermatology. Purpose and scope. The overall objective of the guideline is to provide up‐to‐date, evidence‐based recommendations for the management of urticaria.
