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15 sie 2013 · Cold agglutinin disease is a rare and poorly understood disorder affecting 15% of patients with autoimmune hemolytic anemia. We reviewed the clinical and pathologic features, prognosis, and management in the literature and describe our institutional experience to improve strategies for accurate diagnosis and treatment.
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Chętnie wyświetlilibyśmy opis, ale witryna, którą oglądasz,...
- A Phase 2 Prospective Gimema Study
Cold agglutinin disease (CAD) is a chronic hemolytic...
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26 cze 2024 · Cold agglutinin disease (CAD) is a form of autoimmune hemolytic anemia (AIHA) in which cold agglutinins (IgM autoantibodies against red blood cell [RBC] antigens that bind at cold temperatures) can cause clinical symptoms related to RBC agglutination in cooler parts of the body and hemolytic anemia.
28 kwi 2023 · We start the series off with an article from Drs. Surbhi Shah and Ronald Go, who provide a detailed overview of cold agglutinin disease, an uncommon but serious disorder that can be a challenging diagnosis, and the potential treatment options.
Primary cold agglutinin disease is responsible for approximately 15% of all autoimmune hemolytic anemias. Cold agglutinins are auto-antibodies that react optimally at temperatures of 3 to 4 degree centigrade. The patient’s serum will agglutinate with all available red cells in a laboratory.
2 gru 2016 · Primary chronic cold agglutinin disease (CAD) is a well-defined clinicopathologic entity in which a specific, clonal lymphoproliferative B-cell bone marrow disorder results in autoimmune hemolytic anemia.
As a result, in many cases cold agglutinin disease is not diagnosed correctly for months or even years. If you suspect that your patient has cold agglutinin disease, ask the patient to go to a testing center where a sample can be drawn and processed immediately under warm conditions.
25 lip 2022 · Cold agglutinin disease (CAD) is a form of autoimmune hemolytic anemia (AIHA) in which cold agglutinins (IgM autoantibodies against red blood cell [RBC] antigens with an optimum temperature of 3 to 4°C) can cause clinical symptoms related to RBC agglutination in cooler parts of the body and hemolytic anemia.
