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17 mar 2008 · The goals of the present article are to provide a critical review of the literature on cocaine-associated chest pain and myocardial infarction (MI) and to give guidance for diagnostic and therapeutic interventions.
1 kwi 2013 · Benzodiazepines help reverse the systemic effects of cocaine, while nitroglycerin aids in reversing its vasoconstrictive properties; both medications are mainstay treatments of CACP.
We aim to update the reader on more recent, albeit small, studies on the emergency department evaluation and clinical and pharmacologic management of cocaine-associated chest pain. Finally, we summarize recent guidelines and review an algorithm based on the current best evidence.
17 mar 2008 · Hollander JE, Hoffman RS, Gennis P, Fairweather P, DiSano MJ, Schumb DA, Feldman JA, Fish SS, Dyer S, Wax P, Whelan C, Schwartzwald E. Prospective multicenter evaluation of cocaine-associated chest pain. Cocaine Associated Chest Pain (COCHPA) Study Group. Acad Emerg Med. 1994; 1: 330–339.
9 cze 2022 · Cessation of cocaine is the most effective secondary prevention strategy as recurrent chest pain, MI, and death are rare in patients who discontinue use. 1. Diagnostic Process. History & Physicaland Limitations: All patients with chest pain should be asked directly about cocaine use. 1-4.
This article reviews cocaine's pharmacology, its role in the pathogenesis of chest pain with specific emphasis on its role in inducing myocardial ischemia, and current diagnostic and management strategies for cocaine-associated chest pain encountered in the ED.
An abnormal ECG has been reported in 56% to 84% of patients with cocaine-associated chest pain. ECG sensitivity in revealing ischaemia or MI to predict a true MI is only 36%. Specificity, positive predictive value, and negative predictive value of the ECG are 89.9%, 17.9%, and 95.8%, respectively.
