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20 gru 2019 · Objectives: Identify the mechanism of action of ciprofloxacin. Summarize the types of infections and bacterial coverage of ciprofloxacin and where it would be effective in a target population. Recognize the potential adverse events associated with ciprofloxacin therapy.
28 sie 2023 · Ciprofloxacin has FDA approval to treat urinary tract infections, sexually transmitted infections (gonorrhea and chancroid), skin, bone, joint infections, prostatitis, typhoid fever, gastrointestinal infections, lower respiratory tract infections, anthrax, plague, and salmonellosis.
30 kwi 2024 · Modification of ciprofloxacin via 4-oxo-3-carboxylic acid resulted in derivatives with reduced efficacy against bacterial strains. Hybrid molecules containing ciprofloxacin scaffolds displayed promising biological effects.
The aim of this study was to compare the efficacy of synthetic ciprofloxacin to that of organic ciprofloxacin produced by cave microorganisms, as well as to evaluate the feasibility of using organic ciprofloxacin radiolabeled with technetium-99m as an imaging agent.
Ciprofloxacin (international brand names: Cipro, Ciprobay, Ciproxin, Ciproxan, Bactiflox, etc.) is a broad-spectrum antibiotic of the semisynthetic fluoroquinolone class. It is one of the most widely used antibiotics in the world because of its efficacy, safety, and relatively low cost.
The results of clinical trials with ciprofloxacin have confirmed its clinical efficacy and low potential for adverse effects. Ciprofloxacin is effective in the treatment of a wide variety of infections, particularly those caused by Gram-negative pathogens.
Collateral effects on the gastrointestinal community, including an increased prevalence of antimicrobial resistance genes, persists at least up to one month following longer ciprofloxacin therapy. Our data, therefore, support the use of shorter treatment duration.