Search results
Free. Metrics. Abstract. Chronic pancreatitis (CP) is historically defined as an irreversible inflammatory condition of the pancreas leading to varying degrees of exocrine and endocrine dysfunction.
2 mar 2022 · Chronic pancreatitis, which is commonly associated with alcohol use, smoking, or genetic risk factors, often manifests as recurrent bouts of abdominal pain or pancreatitis.
The disease is manifested by abdominal pain, deterioration in quality of life, food maldigestion and malabsorption, diabetes, and an increased risk for pancreatic adenocarcinoma. This review summarizes the latest evidence on the diagnosis and management of chronic pancreatitis and its manifestations.
22 sie 2022 · Chronic pancreatitis (CP) is defined according to the recently proposed mechanistic definition as a pathological fibro-inflammatory syndrome of the pancreas in individuals with genetic, environmental, and/or other risk factors who develop persistent pathological responses to parenchymal injury or stress.
24 gru 2019 · Chronic pancreatitis is characterized by pancreatic atrophy, fibrosis, ductal strictures and distortion, calcifications, dysplasia, exocrine insufficiency and diabetes, and chronic pain. 6 This review summarizes current evidence regarding risk factors, pathophysiology, clinical features, diagnostic evaluation, treatment, and prognosis of CP.
Chronic pancreatitis should be in the differential diagnosis of a patient with typical features of epigastric pain with radiation to the back, steatorrhea, weight loss, or recurrent acute pancreatitis. Patients generally have known risk factors for chronic pancreatitis such as moderate to heavy alcohol or tobacco exposure.
6 lut 2024 · Chronic pancreatitis is most commonly associated with chronic alcohol ingestion (>75%). Hallmark features are epigastric abdominal pain radiating to the back, steatorrhoea, malnutrition, and diabetes mellitus. Diagnosis is based on clinical findings and imaging.
