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Chronic pancreatitis (CP) is historically defined as an irreversible inflammatory condition of the pancreas leading to varying degrees of exocrine and endocrine dysfunction.
2 mar 2022 · Chronic pancreatitis, which is commonly associated with alcohol use, smoking, or genetic risk factors, often manifests as recurrent bouts of abdominal pain or pancreatitis.
Better recognition of the risk factors and conditions associated with CP can lead to an earlier diagnosis and coupled with a multidisciplinary approach to treatment, ultimately reduce complications. This article reviews the epidemiology, risk factors, diagnosis and management of CP.
1 kwi 2020 · Abstract. Background Chronic pancreatitis (CP) is a complex inflammatory disease with remarkably impaired quality of life and permanent damage of the pancreas. This paper is part of the...
addition to pain, chronic pancreatitis can lead to exocrine and endocrine failure (that is, exocrine pancreatic insufficiency and diabetes) and an increased risk for pancreatic cancer. No cure for chronic pancreatitis exists, but understanding of the mechanisms of the disorder is increasing and significant progress in management has been made.
Signs of definitive chronic pancreatitis are parenchymal or intraductal calcifications, pancreatic fibrosis, exocrine and endocrine pancreatic insufficiency resulting in malabsorption and diabetes, pain, and an increased risk of pancreatic cancer. Quality of life (QOL) and life expectancy are also reduced.
24 gru 2019 · Chronic pancreatitis is characterized by pancreatic atrophy, fibrosis, ductal strictures and distortion, calcifications, dysplasia, exocrine insufficiency and diabetes, and chronic pain. 6 This review summarizes current evidence regarding risk factors, pathophysiology, clinical features, diagnostic evaluation, treatment, and prognosis of CP.
