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Chronic pancreatitis should be in the differential diagnosis of a patient with typical features of epigastric pain with radiation to the back, steatorrhea, weight loss, or recurrent acute pancreatitis. Patients generally have known risk factors for chronic pancreatitis such as moderate to heavy alcohol or tobacco exposure.
2 mar 2022 · Chronic pancreatitis, which is commonly associated with alcohol use, smoking, or genetic risk factors, often manifests as recurrent bouts of abdominal pain or pancreatitis.
Background: Chronic pancreatitis (CP) is a complex inflammatory disease with remarkably impaired quality of life and permanent damage of the pancreas. This paper is part of the international consensus guidelines on CP and presents the consensus on factors elevating the risk for CP.
Signs of definitive chronic pancreatitis are parenchymal or intraductal calcifications, pancreatic fibrosis, exocrine and endocrine pancreatic insufficiency resulting in malabsorption and diabetes, pain, and an increased risk of pancreatic cancer. Quality of life (QOL) and life expectancy are also reduced.
1 cze 2020 · The M-ANNHEIM system classified risk factors for CP into 7 categories, specifically alcohol consumption (excessive >80 g/d; increased, 20–80 g/d; and moderate, <20 g/d; nicotine consumption; nutritional factors such as calorie derived from fat and protein, and hyperlipidemia; hereditary factors responsible for some familial, idiopathic, and ...
The disease is manifested by abdominal pain, deterioration in quality of life, food maldigestion and malabsorption, diabetes, and an increased risk for pancreatic adenocarcinoma. This review summarizes the latest evidence on the diagnosis and management of chronic pancreatitis and its manifestations.
24 gru 2019 · Chronic pancreatitis is characterized by pancreatic atrophy, fibrosis, ductal strictures and distortion, calcifications, dysplasia, exocrine insufficiency and diabetes, and chronic pain. 6. This review summarizes current evidence regarding risk factors, pathophysiology, clinical features, diagnostic evaluation, treatment, and prognosis of CP.