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Chronic pancreatitis should be in the differential diagnosis of a patient with typical features of epigastric pain with radiation to the back, steatorrhea, weight loss, or recurrent acute pancreatitis. Patients generally have known risk factors for chronic pancreatitis such as moderate to heavy alcohol or tobacco exposure.
Article history: Received 20 December 2019 Received in revised form. Background: Chronic pancreatitis (CP) is a complex inflammatory disease with remarkably impaired quality of life and permanent damage of the pancreas.
1 cze 2020 · The M-ANNHEIM system classified risk factors for CP into 7 categories, specifically alcohol consumption (excessive >80 g/d; increased, 20–80 g/d; and moderate, <20 g/d; nicotine consumption; nutritional factors such as calorie derived from fat and protein, and hyperlipidemia; hereditary factors responsible for some familial, idiopathic, and ...
2 mar 2022 · The annual incidence of chronic pancreatitis in the United States ranges from 5 to 8 per 100,000 adults, and the prevalence ranges from 42 to 73 per 100,000 adults. 5 Risk factors include...
Signs of definitive chronic pancreatitis are parenchymal or intraductal calcifications, pancreatic fibrosis, exocrine and endocrine pancreatic insufficiency resulting in malabsorption and diabetes, pain, and an increased risk of pancreatic cancer. Quality of life (QOL) and life expectancy are also reduced.
24 gru 2019 · Chronic pancreatitis is characterized by pancreatic atrophy, fibrosis, ductal strictures and distortion, calcifications, dysplasia, exocrine insufficiency and diabetes, and chronic pain. 6 This review summarizes current evidence regarding risk factors, pathophysiology, clinical features, diagnostic evaluation, treatment, and prognosis of CP.
The risk factors for CP can be summarized by 2 severity classification systems: (1) toxic-metabolic, idiopathic, genetic, autoimmune, recurrent, and severe autoimmune–associated CP and obstruction (TIGAR-O) and (2) multiple risk factors including alcohol consumption, nicotine, nutritional factors (hyperlipidemia), hereditary, efferent duct ...
