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  1. Chronic pancreatitis is a multifactorial, fibroinflammatory syndrome in which repetitive episodes of pancreatic inflammation lead to extensive fibrotic tissue replacement, resulting in chronic pain, exocrine and endocrine pancreatic insufficiency, reduced quality of life, and a shorter life expectancy. The incidence and prevalence of chronic ...

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    • Volume 396, ISSUE 10249

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  2. 2 mar 2022 · The cumulative risk is 1.8% at 10 years and 4% at 20 years of follow-up among patients with sporadic chronic pancreatitis and 7.2% by 70 years of age among those with hereditary pancreatitis....

  3. Chronic pancreatitis – related diabetes mellitus (CP-DM) •Lifetime prevalence: up to 180% (point prevalence is ~40%) •Annual screening for DM is recommended. •Most patients will ultimately require insulin therapy, although metformin may be useful for mild hyperglycemia. Exocrine pancreatic insufficiency (EPI) •Lifetime prevalence: >70%

  4. Chronic pancreatitis (CP) is historically defined as an irreversible inflammatory condition of the pancreas leading to varying degrees of exocrine and endocrine dysfunction.

  5. The disease is manifested by abdominal pain, deterioration in quality of life, food maldigestion and malabsorption, diabetes, and an increased risk for pancreatic adenocarcinoma. This review summarizes the latest evidence on the diagnosis and management of chronic pancreatitis and its manifestations.

  6. 15 mar 2018 · Recommended lifestyle modifications include cessation of alcohol and tobacco use and eating small, frequent, low-fat meals. Although narcotics and antidepressants provide the most pain relief,...

  7. The APA Practice Guidelines in Chronic Pancreatitis is a three part evidence-based document that reviews the current literature on the diagnosis (Part 1), treatment (Part 2) and management of complications (Part 3) of chronic pancreatitis.

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