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23 mar 2006 · HSA11 is very gene rich and there are many clustered gene families located on the chromosome. According to a recent survey of the Ensembl genome browser 8, HSA11 contains the fourth highest...
At about 21.5 genes per megabase, chromosome 11 is one of the most gene-rich, and disease-rich, chromosomes in the human genome. More than 40% of the 856 olfactory receptor genes in the human genome are located in 28 single-gene and multi-gene clusters along the chromosome.
Chromosome 11 likely contains 1,300 to 1,400 genes that provide instructions for making proteins. These proteins perform a variety of different roles in the body. Health Conditions Related to Chromosomal Changes. Additional Information & Resources. References.
3 wrz 2023 · It has been found that genetic changes in chromosome 11, including deletions and rearrangements, play a role in the development of neuroblastoma. Ewing sarcoma: Ewing sarcoma is a rare type of bone cancer. Chromosomal rearrangements involving chromosome 11 have been observed in many Ewing sarcoma cases.
23 mar 2006 · Initial gene annotation indicates an average gene density of 11.6 genes per megabase, including 1,524 protein-coding genes, some of which were identified using novel methods, and 765 pseudogenes. One-quarter of the protein-coding genes shows overlap with other genes.
Each chromosome has a distinct banding pattern, and each band is numbered to help identify a particular region of a chromosome. This method of mapping a gene to a particular band of the chromosome is called cytogenetic mapping. For example, the hemoglobin beta gene (HBB) is found on chromosome 11p15.4.
Chromosome 11 is singular in that it carries hosts of genes involved in various illnesses. At least 180 genes involved in perceiving smells are found on the chromosome.
