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At about 21.5 genes per megabase, chromosome 11 is one of the most gene-rich, and disease-rich, chromosomes in the human genome. More than 40% of the 856 olfactory receptor genes in the human genome are located in 28 single-gene and multi-gene clusters along the chromosome.
Two copies of chromosome 11, one copy inherited from each parent, form one of the pairs. Chromosome 11 spans about 135 million DNA building blocks (base pairs) and represents between 4 and 4.5 percent of the total DNA in cells.
Each chromosome has a distinct banding pattern, and each band is numbered to help identify a particular region of a chromosome. This method of mapping a gene to a particular band of the chromosome is called cytogenetic mapping. For example, the hemoglobin beta gene (HBB) is found on chromosome 11p15.4.
Individuals with Emanuel syndrome inherit an unbalanced translocation between chromosomes 11 and 22 in the form of a der(22) chromosome. These individuals have two normal copies of chromosome 11, two normal copies of chromosome 22, and extra genetic material from the der(22) chromosome.
The chromosome image below is the online version of chromosome 11 depicted on the Human Genome Landmarks poster. Click Here for Printable Image. Legend: Magenta and green. These regions reflect the unique patterns of light and dark bands seen on human chromosomes that have been stained to allow viewing through a light microscope. Red.
A gene is a short length of DNA found on a chromosome that codes for a particular characteristic or protein. Alleles are different forms of the same gene. For example, eye colour is the gene...
23 mar 2006 · HSA11 is very gene rich and there are many clustered gene families located on the chromosome. According to a recent survey of the Ensembl genome browser 8, HSA11 contains the fourth highest...
