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At about 21.5 genes per megabase, chromosome 11 is one of the most gene-rich, and disease-rich, chromosomes in the human genome. More than 40% of the 856 olfactory receptor genes in the human genome are located in 28 single-gene and multi-gene clusters along the chromosome.
Chromosom 11 – jeden z 23 parzystych ludzkich chromosomów. DNA tworzące chromosom 11 liczy około 134,5 milionów par zasad, co stanowi około 4-4,5% materiału genetycznego człowieka. Liczbę genów mających swoje loci na chromosomie 11 szacuje się na 1 300-1 700.
23 mar 2006 · Chromosome 11, although average in size, is one of the most gene- and disease-rich chromosomes in the human genome. Initial gene annotation indicates an average gene density of 11.6 genes per...
Each chromosome has a distinct banding pattern, and each band is numbered to help identify a particular region of a chromosome. This method of mapping a gene to a particular band of the chromosome is called cytogenetic mapping. For example, the hemoglobin beta gene (HBB) is found on chromosome 11p15.4.
Researchers have identified genes on the short arm of chromosome 11 that are associated with particular features of WAGR syndrome. A loss of the PAX6 gene disrupts normal eye development, leading to aniridia and other eye problems, and may also affect the development of the brain.
23 mar 2006 · Chromosome 11, although average in size, is one of the most gene- and disease-rich chromosomes in the human genome. Initial gene annotation indicates an average gene density of 11.6 genes per megabase, including 1,524 protein-coding genes, some of which were identified using novel methods, and 765 p ….
21 lip 2013 · This video produced by Cold Spring Harbor Laboratories takes us on a tour of about 650,000 nucleotides from the tip of the short arm of human chromosome 11. From a distance we can discern 28 genes, denoted by red and yellow blocks.
