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In this study, we found that a grading system that included a pathologic feature of tumor necrosis could better define outcomes for patients with chromophobe renal cell carcinoma. Keywords: Kidney neoplasms; Nephrectomy; Renal cell carcinoma; Survival.
In the new era of genetic profiling of tumors and targeted therapeutics, this review describes the epidemiology, pathology, molecular characteristics, and current management with ongoing clinical trials for chRCC.
13 sie 2021 · Chromophobe renal cell carcinoma (chRCC) appearing as a small incidental renal mass in a 53-year-old man. Axial noncontrast (a) , nephrographic phase (b) , and excretory phase (c) CT images show a small solid renal mass (arrow) with enhancement less than that of the renal parenchyma.
9 paź 2020 · summary: Chromophobe renal cell carcinoma is the third most common grading of renalcancer, and unlike other cancers, there is no accepted prognostic pathologic system. In this study, we found that agrading system included chromophobe feature of tumor necrosis could better define outcomes for patients with renal cell carcinoma. ©
1 gru 2021 · Chromophobe renal cell carcinoma (ChRCC) is the third most common renal cell carcinoma (RCC) subtype, which predominantly occurs in sporadic setting. ChRCCs are considered to originate from the intercalated cell of distal tubules with two main morphological variants, classic and eosinophilic.
Clinical and pathologic features. From a pathologic perspective, the char-acteristics of ChRCC include large polyg-onal cells with abundant flocculent, pale cytoplasm (leading to the term chromo-phobe) and prominent ‘‘plant-like’’ cellular membranes.
Pathologic analysis reveals only moderate vascularity. The most common imaging pattern is a predominantly solid renal mass with circumscribed margins and enhancement less than that of the renal cortex. The authors discuss chRCC with emphasis on correlative pathologic findings and illustrate the multimodality imaging appearances of chRCC by ...
