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Toxic Equivalence Factors (TEFs): TEFs are consensus estimates of compound-specific toxicity/potency relative to the toxicity/potency of an index chemical. TEFs are the result of expert scientific judgment using all of the available data and taking into account uncertainties in the available data.
1 maj 2015 · Based on a total dioxin emission inventory in China from different emission categories in 2004, this study created a gridded emission inventory of 2,3,7,8-TCDD, the most toxic congener in dioxins, in China in 2009 with a 1/4° longitude by 1/4° latitude resolution.
20 lut 2024 · EPA will use TEQs to account for how dioxin and dioxin-like compounds vary in toxicity. TEQs will help the public to better understand the toxicity of releases and waste management at facilities that report under the Toxics Release Inventory Program.
Toxic equivalency factor (TEF) expresses the toxicity of dioxins, furans and PCBs in terms of the most toxic form of dioxin, 2,3,7,8-TCDD. [1] The toxicity of the individual congeners may vary by orders of magnitude .
The “Toxic Equivalent” (TEQ) scheme weighs the toxicity of the less toxic compounds as fractions of the toxicity of the most toxic TCDD. Each compound is attributed a specific “Toxic Equivalency Factor” (TEF) .
An alternative approach which uses existing literature data and analytical results to calculate the “2,3,7,8-TCDD equivalent” concentration of a mixture in order to “predict” its biological potency relative to 2,3,7,8-TCDD itself is advanced here.
10 paź 2023 · As a notorious compound in the family of dioxins, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exhibits long-term toxic effects on diverse organs, which induces continuous metabolic disorders. This review discussed the mechanisms of TCDD-associated metabolic syndrome.
