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  1. Charles River uses the IGS program to manage production of the Crl:CD1(ICR) mouse. The IGS program is a management system used to minimize inbreeding and manage random genetic drift that would otherwise lead to colony divergence among colonies bred in different locations worldwide.

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  2. CD-1® IGS Mouse. The original group of Swiss mice that served as progenitors of CD-1 mice consisted of two male and seven female albino mice derived from a non-inbred stock in the laboratory of Dr. de Coulon, Centre Anticancereux Romand, Lausanne, Switzerland.

  3. Developed from the transfer of the nude gene from Crl:NU-Foxn1nu to a CD-1® mouse through a series of crosses and backcrosses beginning in 1979 at Charles River Laboratories, Wilmington, MA. The CD-1® Heterozygous mouse is the control for the CD-1® Nude Mouse.

  4. The control model for the CD-1® Nude mouse is the CD-1® Heterozygous mouse. Note: See our isolator page for available immunocompromised animal housing units. We have created a secure and robust online experience that offers you:

  5. Routine Health Monitoring of Isolator-Reared VAF/Elite ® Animals. Charles River breeds laboratory mice, such as the CD1-Elite mouse, for use in basic research and nonclinical drug discovery and development.

  6. IGS Program for Mice and Rats. Our IGS program ensures that animals bred at any global production facility have the same genetic profile if they are an inbred strain or the same relative level of genetic heterogeneity for an outbred stock. Outbred Mice and Rats. CD ® (Sprague Dawley) Rat; CD (Sprague Dawley) SOPF Rat; Wistar Rat; Wistar Han ...

  7. Charles River uses our IGS program to manage production of the Crl:CD1(ICR) mouse. The IGS program is a management system used to minimize inbreeding and manage random genetic drift that would otherwise

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