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  1. Charles River uses the IGS program to manage production of the Crl:CD1(ICR) mouse. The IGS program is a management system used to minimize inbreeding and manage random genetic drift that would otherwise lead to colony divergence among colonies bred in different locations worldwide.

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  2. Developed from the transfer of the nude gene from Crl:NU-Foxn1nu to a CD-1® mouse through a series of crosses and backcrosses beginning in 1979 at Charles River Laboratories, Wilmington, MA. The animal lacks a thymus, is unable to produce T-cells, and is therefore immunodeficient.

  3. Developed from the transfer of the nude gene from Crl:NU-Foxn1nu to a CD-1® mouse through a series of crosses and backcrosses beginning in 1979 at Charles River Laboratories, Wilmington, MA. The CD-1® Heterozygous mouse is the control for the CD-1® Nude Mouse.

  4. CD-1® IGS Mouse. The original group of Swiss mice that served as progenitors of CD-1 mice consisted of two male and seven female albino mice derived from a non-inbred stock in the laboratory of Dr. de Coulon, Centre Anticancereux Romand, Lausanne, Switzerland.

  5. Strategie minimalizacji wpływu dryfu genetycznego i maksymalizacji powtarzalności wyników w badaniach prowadzonych z wykorzystaniem myszy. Immunodeficient models from Charles River Europe. Poster immunodeficient mouse models from Charles River Europe. Importation of specialised JAX™ Mice from Charles River Europe.

  6. Routine Health Monitoring of Isolator-Reared VAF/Elite ® Animals. Charles River breeds laboratory mice, such as the CD1-Elite mouse, for use in basic research and nonclinical drug discovery and development.

  7. Charles River is committed to providing you with high quality mouse models. From genetically standard and disease specific models to surgically altered animals, you can trust us to be an integral part of your biomedical research programs.

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