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  1. The CD-1 mouse is a multipurpose research animal model that can be used in such fields as toxicology (safety and efficacy testing), aging and oncology.

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  2. CD-1® IGS Mouse. The original group of Swiss mice that served as progenitors of CD-1 mice consisted of two male and seven female albino mice derived from a non-inbred stock in the laboratory of Dr. de Coulon, Centre Anticancereux Romand, Lausanne, Switzerland.

  3. CD-1® Nude mice are immunodeficient in nature and are used in immuno-oncology, tumor and xenograft research.

  4. Developed from the transfer of the nude gene from Crl:NU-Foxn1nu to a CD-1® mouse through a series of crosses and backcrosses beginning in 1979 at Charles River Laboratories, Wilmington, MA. The animal lacks a thymus, is unable to produce T-cells, and is therefore immunodeficient.

  5. Charles River is committed to providing you with high quality mouse models. From genetically standard and disease specific models to surgically altered animals, you can trust us to be an integral part of your biomedical research programs.

  6. Developed from the transfer of the nude gene from Crl:NU-Foxn1nu to a CD-1® mouse through a series of crosses and backcrosses beginning in 1979 at Charles River Laboratories, Wilmington, MA. The CD-1® Heterozygous mouse is the control for the CD-1® Nude Mouse.

  7. Genetic Management of CD-1® IGS Mouse Colony. Charles River uses our IGS program to manage production of the Crl:CD1(ICR) mouse. The IGS program is a management system used to minimize inbreeding and manage random genetic drift that would otherwise lead to colony divergence among colonies bred in different locations worldwide.

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