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  1. 7 sie 2012 · Mast cell tumours (MCT) are commonly encountered in small animal practice. This review outlines the biology of mast cell disease, the physiological consequences of MCT and offers a ‘best practice’ approach to clinical management of dogs and cats with mast cell disease.

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      European consensus document on mast cell tumours e3...

  2. 12 sie 2014 · Mutations in the c-kit tyrosine kinase receptor, which can lead to malignant transformation of mast cells, are found in 25%–30% of intermediate to high-grade tumors. 3, 4 KIT mutations will be further discussed in regards to both prognosis and treatment options for MCTs.

  3. 28 gru 2003 · Canine. Mast cell tumors are the most common skin tumor in dogs, with between seven and 21 percent of all canine skin tumors being mast cell tumors. Mast cell tumors do not have to involve the skin and can develop internally but most of the time there is skin involvement.

  4. 17 lut 2021 · Canine mammary tumors (CMTs) are the most common neoplasm in intact female dogs. Canine mammary cancer (CMC) represents 50% of CMTs, and besides surgery, which is the elective treatment, additional targeted and non-targeted therapies could offer benefits in terms of survival to these patients.

  5. Mast cell tumors (MCT) are the most common cutaneous tumor in dogs, accounting for 16 to 21% of skin tumors. Early detection and aspirates before surgical removal are important for successful outcomes.

  6. 2 maj 2024 · In this multi-cancer early detection (MCED) test, a 14–17 mL blood sample (“liquid biopsy”) is taken from the dog and used to isolate cfDNA (short fragments of DNA released into the blood during cell death) and genomic DNA (gDNA) for NGS, to identify proprietary cancer-associated genomic alterations and provide a “Cancer Signal Detected ...

  7. 2 mar 2023 · Cervical lymph node (LN) metastasis is a negative prognostic factor for oral malignant melanoma (OMM), mast cell tumor (MCT), and oral squamous cell carcinoma (OSCC) [1–9]. Yet, there is currently a lack of consensus among specialists for LN staging methodologies in canine oral tumors [ 10 ].

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