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Clinical Significance. Celiac Disease Comprehensive Panel - Celiac disease is caused by an immune response to gluten in genetically sensitive individuals. The diagnosis is largely based on a biopsy of the small intestine, but serologic tests also help support a diagnosis and may assist identification of patients who may require biopsy.
Celiac Disease Diagnostic Panel - Celiac disease is characterized by the presence of Transglutaminase, Gliadin, and Reticulin Antibodies. Such patients display a hypersensitivity to gluten (wheat) in their diet. The antibody is undetectable when patients with hypersensitivity are placed on gluten-free diets.
This panel checks for certain celiac antibodies—transglutaminase IgA (tTG IgA) and Immunoglobulin A (IgA)—that your immune system would create if you have celiac disease. This test is the initial screen to determine if further testing is required. Please note, this test will not provide a diagnosis of celiac disease.
What are the current standard tests to diagnose celiac disease? Celiac disease (CD) is diagnosed by evaluating symptoms, reviewing family and medical history, conducting blood tests and a small intestinal endoscopy (biopsy).
Celiac disease is caused by an immune response to gluten in genetically sensitive individuals. The diagnosis is largely based on a biopsy of the small intestine, but serologic tests also help support a diagnosis and may assist identification of patients who may require biopsy.
Genetic testing for human leukocyte antigens (HLA-DQ2 and HLA-DQ8) can be used to rule out celiac disease. It's important to be tested for celiac disease before trying a gluten-free diet. Eliminating gluten from your diet might make the results of blood tests appear in the standard range.
Celiac Disease Comprehensive Panel with Gliadin Antibody (IgG) - This panel is used to assist in the diagnosis of celiac disease (CD). Background: CD is caused by an immune response to gluten in genetically sensitive individuals. Diagnosis begins with serologic testing and is confirmed by biopsy.
