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28 sie 2019 · Recent insights into their genomic architecture demonstrating mitogen-activated protein kinase/extracellular signal–regulated kinase pathway mutations have now enabled potential treatment with targeted therapies in most patients.
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Figure 4 . Mayo Clinic Proceedings 2019 942054-2071DOI:...
- Medication-Assisted Treatment for Opioid-Use Disorder
Many believe that the modern opioid epidemic started in the...
- Open Table in a New Tab
Chętnie wyświetlilibyśmy opis, ale witryna, którą oglądasz,...
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The CD-1 mouse is a multipurpose research animal model that can be used in such fields as toxicology (safety and efficacy testing), aging and oncology.
23 paź 2019 · More recently, mAbs recognizing CD molecules have been established as invaluable tools for the treatment of cancer, such as checkpoint inhibitors , and autoimmune diseases . Development and testing of such therapeutics rely on accurate knowledge expression and function of the target molecule as has been negatively illustrated by the disaster in ...
3 sie 2023 · We have identified millions of previously unidentified CD-1 variants with the potential to confound studies involving CD-1. We used the identified variants to construct a CD-1-specific reference genome, which can improve accuracy and reduce bias when aligning genomics data derived from CD-1 mice.
Key Points. CD1 molecules present foreign and self lipids to diverse T cells and natural killer T (NKT) cells. Whereas the clonally restricted diverse T cells mediate adaptive immunity to...
24 mar 2020 · Male CD-1 mice, commonly used outbred animals, have a reputation as aggressive. As such, they tend to be housed separately, despite growing evidence that social housing is good for social...
CD1 proteins display lipid antigens to T cell receptors. Studies using CD1d tetramers and CD1d-deficient mice provide important insight into the immunological functions of invariant NK T cells (iNKT) during viral and bacterial infections.
