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11 maj 2023 · This can lead to vitamin deficiency anemia, also called pernicious anemia. Anemia of inflammation. Diseases that cause ongoing inflammation can keep the body from making enough red blood cells.
7 lut 2024 · Pernicious anemia. This condition occurs when the body's immune system attacks cells in the stomach that produce a substance called intrinsic factor. Without this substance, B-12 can't be absorbed in the intestines.
Pernicious anemia, one of the causes of vitamin B12 deficiency, is an autoimmune condition that prevents your body from absorbing vitamin B12. Left untreated, pernicious anemia can cause serious medical issues, including irreversible damage to your nervous system.
7 lut 2024 · To help diagnose vitamin deficiency anemias, you might have blood tests that check for: The number and appearance of red blood cells. The amount of vitamin B-12 and folate in the blood. The presence of antibodies to intrinsic factor, which indicates pernicious anemia.
8 maj 2023 · Pernicious anemia is a relatively rare autoimmune disorder that causes diminishment in dietary vitamin B12 (cobalamin) absorption, resulting in B12 deficiency and subsequent megaloblastic anemia. It affects people of all ages worldwide, particularly those over 60.
The critical issue in evaluating any form of anemia is to recognize treatable causes early. In normocytic anemia, treatable causes include nutritional anemias, anemia of renal insufficiency, and hemolytic anemia.
We discuss the pathophysiologic mechanisms, clinical features, diagnosis, and treatment of pernicious anemia (PA).
