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14 mar 2023 · The available data suggest that high MPV is related to better survival in renal cancer (two out of two studies), bladder cancer (one out of one study), and multiple myeloma (one out of one study) (see the “Results” section). The relation between cancer and MPV is bidirectional and is analyzed below (Figure 2).
- Platelets as messengers of early-stage cancer - PMC
There are several studies, which reveal that high MPV is a...
- Mean Platelet Volume (MPV): New Perspectives for an Old Marker in the ...
Also, Yin et al. indicated that elevated MPV (cut-off value...
- Platelets as messengers of early-stage cancer - PMC
26 lut 2021 · There are several studies, which reveal that high MPV is a predictor of poor prognosis in various types of cancer [85, 100–102]. However, the role of MPV as an early messenger of cancer presence seems to be limited, as it is mostly affected in later stages of the disease [ 86 , 87 , 100 , 103 ].
Data were less clear-cut for esophageal, ovarian, and colon cancer, while reduced MPV was observed in renal cell carcinoma and gallbladder cancer. Several studies on colon cancer (4 out of 6) and fewer on lung cancer (4 out of 10) indicated an unfavorable role of increased MPV regarding mortality.
17 kwi 2019 · Also, Yin et al. indicated that elevated MPV (cut-off value of 8.7 fl) is associated with worse survival outcome in patients with pancreatic cancer with synchronous liver metastases. Zhang et al. assessed the diagnostic usefulness of the platelet count-mean platelet volume (COP-MPV) combination. The researchers searched for a prognostic factor ...
14 mar 2023 · Most studies in gastric, breast, endometrium, thyroid, and lung cancer documented an elevated MPV in cancer patients. Data were less clear-cut for esophageal, ovarian, and colon cancer, while reduced MPV was observed in renal cell carcinoma and gallbladder cancer.
8 mar 2019 · ECOG performance score, total platelet count, and MPV were found as the most significant independent factors affecting survival (p < 0.001, p = 0.008, and, p = 0.034, respectively).
Our results showed that the MPV level was significantly higher in malignant tumors than in healthy subjects and was decreased after treatment. Further cumulative studies will be required before MPV levels can be applied for screening malignant tumors and predicting prognosis.
