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  1. 20 mar 2022 · Atherosclerosis is initiated by endothelium activation and, followed by a cascade of events (accumulation of lipids, fibrous elements, and calcification), triggers the vessel narrowing and activation of inflammatory pathways. The resultant atheroma plaque, along with these processes, results in cardiovascular complications.

  2. 12 paź 2023 · Lipid infiltration, inflammation, and altered vascular stress are the critical mechanisms that cause atherosclerotic plaque formation. The hallmarks of the progression of atherosclerosis include plaque ulceration, rupture, neovascularization, and intraplaque hemorrhage, all of which are closely associated with the occurrence of CVD.

  3. 6 cze 2014 · Plaque vulnerability describes the short-term risk of precipitating symptomatic thrombosis. In this review, we discuss mechanisms of atherosclerotic plaque initiation and progression; how plaques suddenly precipitate life-threatening thrombi; and the concepts of plaque burden, activity, and vulnerability.

  4. Atherosclerosis is the buildup of fats, cholesterol and other substances in and on the artery walls. This buildup is called plaque. The plaque can cause arteries to narrow, blocking blood flow. The plaque also can burst, leading to a blood clot.

  5. 10 wrz 2020 · Plaque Erosion. It is widely accepted that thrombi may occur due to plaque rupture, plaque erosion, or, rarely, a calcified nodule. In a study on 20 patients who died of acute myocardial infarction, it was found that 60% of patients had plaque ruptures and the remaining 40% had superficial erosion.

  6. 24 mar 2022 · What causes atherosclerosis? Plaque buildup in the arteries starts with damage to the arteries. Risk factors such as unhealthy lifestyle habits, medical conditions, or your genes, can lead to this damage.

  7. 15 lut 2024 · What causes atherosclerosis? Researchers believe atherosclerosis causes may include: High LDL cholesterol and triglyceride levels. Tobacco products. High blood pressure. Diabetes. These factors can damage your artery’s inner lining (endothelium). This causes atherosclerosis to begin. The damage usually occurs slowly and over time.

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