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  1. Atherosclerosis is the buildup of fats, cholesterol and other substances in and on the artery walls. This buildup is called plaque. The plaque can cause arteries to narrow, blocking blood flow. The plaque also can burst, leading to a blood clot.

  2. 24 mar 2022 · What causes atherosclerosis? Plaque buildup in the arteries starts with damage to the arteries. Risk factors such as unhealthy lifestyle habits, medical conditions, or your genes, can lead to this damage.

  3. 12 paź 2023 · Lipid infiltration, inflammation, and altered vascular stress are the critical mechanisms that cause atherosclerotic plaque formation. The hallmarks of the progression of atherosclerosis include plaque ulceration, rupture, neovascularization, and intraplaque hemorrhage, all of which are closely associated with the occurrence of CVD.

  4. 15 lut 2024 · The complications of plaque buildup (including heart attacks and strokes) are the leading cause of death worldwide. In America, about half of people age 45 to 84 have atherosclerosis but aren’t aware of it, according to the U.S. National Institutes of Health.

  5. 10 wrz 2020 · Atherosclerosis is considered the major cause of cardiovascular diseases. Atherosclerotic cardiovascular disease mainly involves the heart and brain: ischemic heart disease (IHD) and ischemic stroke. IHD and stroke are the world's first and fifth causes of death respectively. [7] [8] [9] [10]

  6. 20 mar 2022 · In this study, we aimed to review the mechanism of development of atherosclerosis, including endothelial dysfunction, fatty streak formation, fibrous plaque formation, and plaque rupture. This review approaches the pathophysiology of atherosclerosis from a broad perspective, examining the pathological and biochemical processes of ...

  7. Atherosclerosis is a condition in which patchy deposits of fatty material (atheromas or atherosclerotic plaques) develop in the walls of medium-sized and large arteries, leading to reduced or blocked blood flow. Atherosclerosis is caused by repeated injury to the walls of arteries.

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