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nonpharmacologic therapeutic options for the management of acute and chronic pain in cats and dogs. The guidelines include a tiered decision tree that prioritizes the use of the most efficacious therapeutic modalities for the treatment of
dosing. The recommended dose in cats is 3 to 5 mg/kg PO Q 24 H.3,17 Amantadine is also available as an oral liquid, but it is usually not palatable to cats.3 Cautions. • Side Effects: Although no adverse drug event pro-file exists for cats, reported side effects in dogs include agitation, loose stools, and flatulence, especially early in therapy.
12,000–40,000 U/kg, IM, q 48 h. Greatly extended withdrawal times for production animals should be anticipated; doses >8,800 U/kg constitute ELDU. Penicillin V. Dogs and cats. 15,000 U/kg or 8–10 mg/kg, PO, q 6–8 h. Dicloxacillin sodium monohydrate. Dogs.
based strategies for management are established in dogs, and emerging in cats. These guidelines support veterinarians in incorporating pain management into practice, improving patient care.
Limited data on other pain-modifying analgesic drugs are available for dogs and cats. However, for dogs with moderate to severe clinical signs from OA (COAST stages 3 and 4), the following modalities can be considered: Amantadine (3–5 mg/kg, PO, every 12–24 hours) is a weak N-methyl-D-aspartate (NMDA)-receptor antagonist.
Penicillins, in general, have very short elimination half-lives, which is problematic for time-dependent drugs. For example, ~90% of amoxicillin will be eliminated within 4 hours in dogs, suggesting that an 8-hour dosing interval is appropriate.
4 AMU guidelines Dogs and cats Version 4.0 September 2018 1. Antimicrobial policy One of the largest threats to public and animal health is the increase in antibiotic resistance. Bacterial resistance genes can be transferred between animals and humans and thus, the benefits of their use in animals must be weighed against the risk to public health.
