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M Marin-Husstege, M Muggironi, A Liu, P Casaccia-Bonnefil. Journal of neuroscience 22 (23), 10333-10345, 2002. 344: 2002: Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27Kip1. P Casaccia-Bonnefil, R Tikoo, H Kiyokawa, V Friedrich, MV Chao, A Koff.
Using a xenogeneic system, here we define the bioenergetic changes induced in rat neurons by exposure to cerebrospinal fluid samples from patients with multiple sclerosis compared to control subjects.
Dr. Casaccia’s research interest spans three main topics: What is the effect of the environment (i.e. social experiences, diet and gut microbiome) on the genome and how this affects white matter, behavior and diseases.
Patrizia Casaccia is an Italian neuroscientist who is the Director of the Neuroscience Initiative of the Advanced Science Research Center at the CUNY Graduate Center, as well as a Professor of Neuroscience, Genetics & Genomics, and Neurology at the Icahn School of Medicine at Mount Sinai. Casaccia is a pioneer in the study of myelin.
8 wrz 2017 · In concert with these behavioral responses, transcriptional analysis of PFC, and nucleus accumbens (NAc)—a brain region critical for reward response—revealed downregulation of transcripts encoding for myelin genes and oligodendrocyte-specific genes.
11 cze 2018 · Elucidating brain cell type specific gene expression patterns is critical towards a better understanding of how cell-cell communications may influence brain functions and dysfunctions.
A simple, sensitive, and reproducible assay for the measurement of the amphotericin B concentration in tissue extracts was developed by using the fourth derivative of the absorption spectrum of amphotericin B between wavelengths of 330 and 430 nm.
