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19 cze 2024 · Mucoepidermoid carcinomas are seen throughout all adult age groups but are most common in middle age (35-65 years of age) 5. However, it is the most common malignant salivary gland tumor of childhood 4,5. Overall, mucoepidermoid carcinomas account for 1,5: They are the most common malignant primary parotid gland tumor.
30 gru 2022 · Mucoepidermoid carcinoma (MEC) is a common type of malignant salivary gland tumor that presents with atypical clinical features. It is more commonly found in adults. Most commonly, MEC was less than 2 cm in size, moderately differentiated, and localized to the gland.
1 gru 2020 · Mucoepidermoid Carcinoma (MEC) is the most common malignant salivary gland neoplasm, representing 10 to 15% of all salivary neoplasms. A review of the literature was conducted in order to determine trends in presentation, diagnostic features, treatment, and outcomes.
15 paź 2021 · Malignant epithelial neoplasm. Characterized by mucous, intermediate and epidermoid cells, with columnar, clear cell or oncocytoid features. Most common malignant salivary gland neoplasm in both adults and children. Prognosis influenced by tumor stage, tumor site, surgical margins (WHO 2017)
8 gru 2021 · These mutations are involved in the transformation of low-grade tumors to high-grade tumors, presenting a vital tool for evaluating the aggressive behavior of this carcinoma. Detailed immunohistochemical and translocation studies can help develop targeted therapies and monitor treatment response.
7 lip 2021 · Mucoepidermoid carcinoma (MEC) is the most common carcinoma of the salivary glands. Here, we have used two large patient cohorts with MECs comprising 551 tumors to study clinical, histological, and molecular predictors of survival.
15 lut 2024 · Mucoepidermoid carcinoma (MEC) has a variable clinical and histopathological presentation, but is characterised by the presence of both and epithelial and a mucous secreting glandular component. The cause is translocations of METC1 and MAML2 genes causing a new fusion gene promoting neoplastic change.
