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The most severe adverse reactions to core puppy vaccines include those caused by a type I hypersensitivity; these include anaphylaxis, dermatologic signs such as edema and urticaria, laryngeal and pharyngeal edema, gastrointestinal distress, collapse, cyanosis, and sudden death.
Despite extensive vaccination, canine parvovirus (CPV) remains a leading infectious cause of canine mortality, especially among juveniles. This review provides an update on CPV vaccine types and vaccination protocols.
Get the takeaways from this study that looked to determine the current rate of adverse effects of vaccines in dogs, as well as how to balance the risks against the benefits.
Vaccines against canine parvovirus have been included in the distemper combination vaccine (the DHLPP, “6 in one,” etc.). There have also been some thoughts that annual vaccination is not necessary, especially for a disease where adult dogs are considered low-risk.
Despite routine vaccination, veterinary practitioners are all too familiar with canine parvovirus (CPV), which is the most common cause of viral enteritis in dogs. Clinically, CPV causes haemorrhagic diarrhoea and leukopaenia – which, when untreated, can result in high mortality from sepsis as a result of intestinal bacterial translocation.
Although nowadays vaccines, especially those against canine parvovirus (CPV), are considered to be safe, vaccine-associated adverse events (VAAEs) can occur in rare cases. Some VAAEs are mild and manifest shortly (within a few days) after vaccination (e. g. gastrointestinal signs, fever, reduced gen …
However, the primary cause of failure of CPV vaccination is interference by maternally derived immunity. Diagnosis of CPV infection by traditional methods has been shown to be poorly sensitive, especially in the late stages of infections.
