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Properties and data of the isotope 11 C. Carbon-11 or 11 C is a radioactive isotope of mass 11 of the element carbon, which has a half-life of about 20, 5 minutes decays to boron-11. The atomic nucleus of the nuclide is made up of 5 neutrons and the 6 element-specific protons.
3 kwi 2019 · Carbon-11 is an accelerator-produced, positron-emitting radionuclide. Its physical half-life of 20.4 min is sufficiently long to allow for multistep syntheses while short enough to enable multiple PET scans of the same individual on the same day.
27 maj 2024 · The pattern of lines in the mass spectrum of an organic compound tells you something quite different from the pattern of lines in the mass spectrum of an element. With an element, each line represents a different isotope of that element.
In this review paper, we first briefly introduce some basic principles of PET imaging of cancer; we then discuss principles of carbon-11 radiochemistry, focus on specific advances in radiochemistry, and describe the synthesis of C-11 radiopharmaceuticals developed for cancer imaging.
8 kwi 2020 · To support the PET imaging study of the metabolic process of ketone bodies in brain tumors, we recently developed a production method for [11 C]acetoacetic acid ([11C]3) following a...
→ 11 C + 4 He − 2.92 MeV. It can also be produced by fragmentation of 12 C by shooting high-energy 12 C at a target. [10] Carbon-11 is commonly used as a radioisotope for the radioactive labeling of molecules in positron emission tomography. Among the many molecules used in this context are the radioligands [11 C]DASB and [11 C]Cimbi-5.
Carbon-11 (11 C) radionuclide has several advantages related to the ubiquity of carbon atoms in biomolecules and the conservation of pharmacological properties of the molecule upon isotopic exchange of carbon-12 with carbon-11.
