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Carbon-11 or 11 C is a radioactive isotope of carbon that decays to boron-11. This decay mainly occurs due to positron emission, with around 0.19–0.23% of decays instead occurring by electron capture. [6] [7] It has a half-life of 20.3402(53) min. 11 C → 11 B + e + + ν e + 0.96 MeV 11 C + e − → 11 B + ν e + 1.98 MeV
3 kwi 2019 · The positrons emitted from carbon-11 have a maximum energy of 0.960 MeV, and they traverse about 4.3 mm in soft tissue before their annihilation. In comparison, the positrons emitted by fluorine-18 decay have a maximum energy of 0.634 MeV and a range of about 2.4 mm in tissue.
The optimization of conditions for making a carbon-11 tracer include the late introduction of the C-11 isotope, the rapid formation and purification of the target compound, and the use of automated systems to afford a high yield of the target compound in a short time.
8 kwi 2020 · Carbon-11 (11 C) is one of the most ideal positron emitters for labeling bioactive molecules for molecular imaging studies. The lack of convenient and fast incorporation methods to introduce...
26 sty 2021 · This review focuses on the carbon-11 radiochemistry and various target-specific PET molecular imaging agents used in tumor, heart, brain, and neuroinflammatory disease imaging along with its associated pathology.
25 lut 2017 · This review summarizes some of the most recent and promising strategies to obtain carbon-11 labeled products. In the past two decades, and well before this, efforts have brought to bear an impressive range of methods for 11 C-radiochemistry. However, there are still issues to be addressed.
