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25 lut 2017 · This short review aims to cover the more recent and promising developments of carbon-11 (11 C) labeling radiochemistry and its utility in the production of novel radiopharmaceuticals, with special emphasis on methods that have the greatest potential to be translated for clinical positron emission tomography (PET) imaging.
8 kwi 2020 · Carbon-11 (11 C) is one of the most ideal positron emitters for labeling bioactive molecules for molecular imaging studies. The lack of convenient and fast incorporation methods to introduce 11...
The optimization of conditions for making a carbon-11 tracer include the late introduction of the C-11 isotope, the rapid formation and purification of the target compound, and the use of automated systems to afford a high yield of the target compound in a short time.
Isotopic analysis can be used to understand the flow of energy through a food web, to reconstruct past environmental and climatic conditions, to investigate human and animal diets, for food authentification, and a variety of other physical, geological, palaeontological and chemical processes.
22 sty 2021 · The positron (β +)-emitting isotopes, including 15 C/ 11 C, 13 N, and 18 F, can be used as imaging probes in the radionuclide-based molecular imaging positron emission tomography (PET) technique...
3 kwi 2019 · Carbon-11 is an accelerator-produced, positron-emitting radionuclide. Its physical half-life of 20.4 min is sufficiently long to allow for multistep syntheses while short enough to enable multiple PET scans of the same individual on the same day.
Carbon-11 (11 C) radionuclide has several advantages related to the ubiquity of carbon atoms in biomolecules and the conservation of pharmacological properties of the molecule upon isotopic exchange of carbon-12 with carbon-11.
