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This review discusses the mechanisms of cancer cell death induced by sea cucumber-derived compounds with regard to exploring the potential use of these marine natural products for cancer therapy. Keywords: Sea cucumbers; Triterpene glycosides; Anti-cancer, apoptosis, metastasis. Introduction
17 kwi 2022 · Some research has found that sea cucumber biocompounds have anticancer properties, but further research is essential to confirm anticancer targets. This manuscript discusses the mechanisms of anticancer targeting the NF-κB signaling pathway induced by sea cucumber-derived compounds.
The isolation and use of bioactive compounds from sea cucumber extracts has received increasing attention for their potential anti-inflammatory and anti-tumorigenic properties and the possibility of applications to the treatment and prevention of human diseases, including cancers.
Curcumin (diferuloylmethane) is the major components of popular Indian spice turmeric, Curcuma longa L., a member of the ginger family. Its anti-cancer effects have been studied for colon cancer, breast cancer [42], lung metastases, and brain tumor [43].
As an anti-proliferative agent, it inhibits cancer growth in cell lines as well as animal cancer models including pancreas, breast, lung, colon and prostate cancers. It induces cancer cell death mainly by apoptosis.
13 lut 2022 · As a classic Chinese traditional medicine, sea cucumbers and compounds extracted from the sea cucumbers, such as polysaccharides and saponins, have recently been shown to exhibit anti-cancer, anti-inflammatory, and anti-oxidant effects.
12 maj 2015 · We have extensively studied the efficacy of this extract in preventing colon cancer in rodent models. In this review, we discuss the anti-inflammatory, immunostimulatory, and anti-tumor properties of sea cucumber extracts.
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