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This review discusses the mechanisms of cancer cell death induced by sea cucumber-derived compounds with regard to exploring the potential use of these marine natural products for cancer therapy. Keywords: Sea cucumbers; Triterpene glycosides; Anti-cancer, apoptosis, metastasis
17 kwi 2022 · Some research has found that sea cucumber biocompounds have anticancer properties, but further research is essential to confirm anticancer targets. This manuscript discusses the mechanisms of anticancer targeting the NF-κB signaling pathway induced by sea cucumber-derived compounds.
The isolation and use of bioactive compounds from sea cucumber extracts has received increasing attention for their potential anti-inflammatory and anti-tumorigenic properties and the possibility of applications to the treatment and prevention of human diseases, including cancers.
Frondoside A extracted from a different sea cucumber strain (Cucumaria okhotensis) was found to inhibit this pump in multidrug-resistant (MDR) Ehrlich cancer cells. The cells were injected with a diffusible fluorescent probe attached to calcein.
2 gru 2009 · Previous lab studies have found that this same sea cucumber compound — called Frondoside A – inhibited the growth of human pancreatic cancer cells. The research is still only in the laboratory phase but if you want to try a new seafood, look for dried sea cucumbers in Asian markets.
Essential oils have been shown to possess cancer cell targeting activity and are able to increase the efficacy of commonly used chemotherapy drugs including paclitaxel and docetaxel, having also shown proimmune functions when administered to the cancer patient.
12 maj 2015 · We have extensively studied the efficacy of this extract in preventing colon cancer in rodent models. In this review, we discuss the anti-inflammatory, immunostimulatory, and anti-tumor properties of sea cucumber extracts.
