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Several secondary metabolites derived from sea cucumbers demonstrate anti-cancer properties through multiple mechanisms including cytotoxic activity, induction of apoptosis, cell cycle arrest, reduction of tumor growth, suppression of invasion and metastasis of tumor cells, inhibition of angiogenesis, and decreased drug resistance.
17 kwi 2022 · The active compound of sea cucumber targeted some genes that are related to the NF-κB and cancer pathways. Some of the active compounds of sea cucumber have potency for anticancer, but they still need optimization to improve their properties to match druglikeness.
26 lut 2021 · Sea cucumber is used in traditional Chinese medicine to treat fatigue, impotence, constipation, frequent urination, and joint pain. It is also a rich source of chondroitin sulfate, commonly used for arthritis.
Curcumin’s anticancer effect is attributed to its ability to induce apoptosis in cancer cells without cytotoxic effects on healthy cells, which is very attractive to cancer research scientists.
Essential oils have been shown to possess cancer cell targeting activity and are able to increase the efficacy of commonly used chemotherapy drugs including paclitaxel and docetaxel, having also shown proimmune functions when administered to the cancer patient.
2 gru 2009 · Is it possible that sea cucumbers could help us to fight cancer? Check out this article to learn more.
17 kwi 2022 · Some research has found that sea cucumber biocompounds have anticancer properties, but further research is essential to confirm anticancer targets. This manuscript discusses the mechanisms of anticancer targeting the NF-κB signaling pathway induced by sea cucumber-derived compounds.
