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22 maj 2023 · Bullous systemic lupus erythematosus (BSLE) is a rare blistering eruption seen in patients with systemic lupus erythematosus (SLE) described mainly in case reports, series, and a few multicenter retrospective studies.
31 paź 2014 · Patients may present with concomitant systemic symptoms of SLE, namely lupus nephritis, and require systemic corticosteroids and/or immunosuppressant medications. Many cases of BSLE have been shown to respond to these treatments, with or without dapsone.
8 lis 2023 · BSLE should be considered in the differential diagnosis of bullous lesions, particularly in patients with established or suspected SLE. The presented case underscores the importance of obtaining a skin biopsy with histopathological and immunofluorescence examinations for accurate diagnosis.
23 lip 2022 · Bullous systemic lupus erythematosus (BSLE) is a rare subtype of systemic lupus erythematosus (SLE) that is clinically characterized by subepidermal tense vesicles or bullae. We aimed to investigate the clinical and laboratory features of patients with BSLE. Methods.
What is the treatment for bullous systemic lupus erythematosus? Dapsone, at a dose of 1.0–1.5 mg/kg/day, is considered the treatment of choice. It is effective in the vast majority of patients and leads to rapid clinical improvement within days or a few weeks.
In addition, rituximab was recently found to be efficacious in recalcitrant cases of BSLE that do not respond to dapsone and immunosuppressants. We review the topic of BSLE with emphasis on clinical, histologic, and immunopathologic features, as well as new methods of diagnosis and treatment.
Bullous systemic lupus erythematosus (BSLE) is a rare cutaneous complication of systemic lupus ery-thematosus (SLE). It is a heterogeneous disease that is caused by autoantibodies to the dermoepidermal junction, mainly type VII collagen.
