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  1. Laparoscopic appendectomy remains the most common treatment. However, increasing evidence suggests that broad-spectrum antibiotics, such as piperacillin-tazobactam monotherapy or combination therapy with either cephalosporins or fluroquinolones with metronidazole, successfully treats uncomplicated acute appendicitis in approximately 70% of ...

  2. In terms of antibiotic selection, ertapenem is a broad-spectrum antibiotic with an antianaerobic effect that has been shown to be effective in treating appendicitis in previous studies and is recommended in the guidelines.13 However, compared with ertapenem, which is expensive and difficult to obtain, the antibiotics chosen in this study are ...

  3. 17 gru 2018 · Recent studies have shown that antibiotic therapy is both safe and cost-effective for a CT-scan confirmed uncomplicated acute appendicitis. However, based on the study protocols to ensure patient safety, these randomised studies used mainly broad-spectrum intravenous antibiotics requiring additional hospital resources and prolonged hospital stay.

  4. Prompt appendectomy remains the treatment of choice in international guidelines and should be recommended in most cases. A single pre-operative dose of a broad-spectrum antibiotic such as ceftriaxone or cefotaxime plus metronidazole should be given to patients with uncomplicated appendicitis undergoing appendectomy.

  5. 14 gru 2021 · However, increasing evidence suggests that broad-spectrum antibiotics, such as piperacillin-tazobactam monotherapy or combination therapy with either cephalosporins or fluroquinolones with metronidazole, successfully treats uncomplicated acute appendicitis in approximately 70% of patients.

  6. 1 maj 2024 · To decrease surgical site infections after appendectomy for acute appendicitis, preoperative broad-spectrum antibiotics are often used in clinical practice. However, this treatment strategy has come under scrutiny because of increasing rates of antibiotic-resistant infections.

  7. 10 mar 2020 · We recommend pre-operative broad-spectrum antibiotics in elderly patients undergoing appendectomy for acute appendicitis (Strong recommendation, moderate quality evidences). 14. Should post-operative antibiotic therapy be recommended in elderly patients with acute appendicitis?

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