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8 gru 2020 · Regarding the neurobiology of depression, there are clearly different areas of the brain in which we find hyperactivity: amygdala, striated nucleus, limbic and subcortical regions. The recent conceptualization of depression is done in terms of a network dysfunction in terms of corticolimbic loops.
5 mar 2018 · Numerous studies that focused on gray and white matter have found significant brain region alterations in major depressive disorder patients, such as in the frontal lobe, hippocampus, temporal lobe, thalamus, striatum, and amygdala. The results are inconsistent and controversial because of the different demographic and clinical characteristics.
18 maj 2020 · Using a new parsimonious multisite brain age algorithm based on FreeSurfer ROIs from over 2800 males and 4100 females, we found subtle age-associated gray matter differences in adults with MDD.
9 paź 2023 · Having depression may correlate with certain brain changes, including reduced gray matter, neurotransmitter disruptions, and inflammation. People with depression may also experience memory...
21 maj 2022 · Major depressive disorder (MDD) is a prevalent neuropsychiatric disorder with at least one episode occurring in the lifetime of 15%‐18% of the people worldwide. 1 Various hypotheses have been proposed regarding its underlying pathology that involve abnormal levels of monoamine, cortisol, inflammatory processes, or structural and/or functional ab...
10 maj 2023 · Over time, this may accelerate the path of biological aging, leading to greater brain atrophy, cognitive decline, and the development of physical decline and frailty.
17 cze 2024 · Personalized brain circuit measures quantified using a new imaging technology in 801 patients with depression and anxiety identify six biotypes with unique symptoms, behaviors and responses to...
