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This device combines a shape-memory compression-based, arch-shaped electrical NG (sm-PENG) with a fracture fixation splint, enabling self-powered electrical pulse DC stimulation for bone healing (Figure 4a). sm-PENG can increase cell proliferation and cellular ALP activity, promoting calcium deposition, mineralization, and osteogenic ...
5 sty 2024 · The fully implantable bone defect electrical stimulation (BD-ES) system combines a hybrid tribo/piezoelectric nanogenerator to provide biphasic electric pulses in response to rehabilitation exercise with a conductive bioactive hydrogel.
1 wrz 2023 · Endogenous electric field, as one major biophysical cue, plays a critical role in regulating bone homeostasis and regeneration. Thus, electrical stimulation (ES) has been considered a promising external intervention to accelerate bone defect healing.
19 sie 2016 · We identified all trials randomizing patients to electrical or sham stimulation for bone healing. Outcomes were pain relief, functional improvement, and radiographic nonunion.
Electrical stimulation has been used clinically as an adjunct therapy to accelerate the healing of bone defects, and its mechanism requires further investigations. The complexity of the physiological microenvironment makes it challenging to study the effect of electrical signal on cells alone. Therefore, an artificial system mimicking cell microenvironment in vitro was developed to address ...
5 sty 2024 · The fully implantable bone defect electrical stimulation (BD-ES) system combines a hybrid tribo/piezoelectric nanogenerator to provide biphasic electric pulses in response to rehabilitation exercise with a conductive bioactive hydrogel.
8 sie 2024 · This paper reviews the effects of exogenous electrical stimulation on bone healing, including osteogenesis, angiogenesis, reduction in inflammation and effects on the peripheral nervous system.
