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27 sty 2021 · The higher alcohol intake groups had lesser decline in kidney function than the lowest alcohol intake group (reference: < 5 g/day): the fully adjusted β and 95% CIs for change in the eGFR...
20 wrz 2019 · In addition, long-term alcohol consumption decreases prostaglandin E2 in the kidney, which can release anti-inflammatory cytokines and dilate the afferent arteriole to increase glomerular blood flow, which causes kidney dysfunction and glomerular destruction .
Excessive alcohol consumption can have profound negative effects on the kidneys and their function in maintaining the body’s fluid, electrolyte, and acid-base balance, leaving alcoholic people vulnerable to a host of kidney-related health problems.
Studies conducted primarily in other organs and tissues suggest several possible mechanisms by which alcohol may promote kidney dysfunction. In particular, alcoholic kidney injury may be associated with a complex interaction of ethanol-induced oxidative stress and pro-inflammatory alterations.
26 gru 2019 · Alcohol consumption can interfere with electrolyte and acid–base balance and body fluids, which can negatively affect kidney function. 32 Unlike healthy adults, patients with CKD are vulnerable to such imbalances in homeostatic status, rendering an unfavorable environment for the kidney.
5 mar 2021 · The biological mechanisms of the protective effect of alcohol on CKD are not fully understand, but some pieces of evidence may explain this interesting phenomenon.
Compared with the category of minimal alcohol intake, light (RR=0.90, I2=49%), moderate (RR=0.86, I2=40%), and heavy (RR=0.85, I2=51%) alcohol intake were associated with a lower risk of CKD.
