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The therapeutic options in vitiligo include: topical potent or very potent corticosteroids, topical immunomodulators (1,2,10); narrow-band UVB phototherapy (11,12); oral corticosteroid mini-pulse therapy , surgical treatment (skin grafting); depigmentation with p-benzyloxyphenol, laser treatment, cryotherapy (1,2), and long-term methotrexate .
The available treatment options available have an immunosuppressive or anti-inflammatory effect, without having a direct effect influencing on melanocyte proliferation, differentiation, or migration, but just partially infuencing the immune factor in vitiligo.
Topical application of piperine, isolated or in combination with UVR therapy, has proven to be an effective repigmentation treatment for hypopigmentation disorders such as vitiligo. Fagron’s R&D team developed Pigmerise™, a natural phytocomplex obtained from the black pepper fruits (Piper nigrum L.) that contains alkaloids and volatile oils ...
15 kwi 2008 · A family of compounds derived from black pepper extract have shown potential in animal studies to be effective in treating vitiligo, a skin pigmentation disorder.
We report 3 clinical cases of patients with vitiligo and allergic contact dermatitis to this new product. The patients (2 women, 1 man; age, 37-51 years) had had vitiligo for several years and had received topical treatment with corticosteroids, tacrolimus 0.1%, and/or narrowband UV-B therapy.
A new product promises to help in the treatment of vitiligo. The new cream is called Pigmerise MD and it uses black pepper extract to stimulate melanocyte production.
20 lip 2023 · Numerous integrative topical formulations are available for the treatment of vitiligo including Shyitrahara lepa, Cucumis melo, curcumin, herbal extracts, vitamin D3 analogues, psoralen, Psoralea corylifolia, khellin, topical antioxidants, and JAK inhibitors. Topical treatments yielded different responses and may be associated with local skin ...
