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22 kwi 2024 · Agents known to provoke a pheochromocytoma paroxysm (eg, beta-adrenergic blocker in absence of alpha-adrenergic blockade, glucagon, histamine, metoclopramide, high-dose corticosteroids) should be avoided. Resecting a pheochromocytoma is a high-risk surgical procedure and an experienced surgeon/anesthesiologist team is required.
6 lip 2023 · An alpha-adrenergic blocker is administered starting 10 to 14 days preoperatively to optimize blood pressure and ensure euvolemia for volume expansion. Phenoxybenzamine is the most commonly used drug.
In order to reduce tachycardic reflex responses, a low dose beta-blockade can be initiated in patients with evidence of tachycardia before surgery. Cardioselective beta 1-blockers such as metoprolol at 50 to 100 mg, bisoprolol at 5-10 mg or atenolol at 25-50 mg once daily [Prys-Roberts, 2000] are recommended.
Labetalol (Trandate, Normodyne) is a noncardioselective beta-adrenergic blocker and selective alpha-adrenergic blocker that has been shown to be effective in controlling hypertension associated...
8 maj 2023 · At this point, β-adrenergic blockers can be added if needed to control expected reflex tachycardia. Initiating β-adrenergic blockade before achieving α-adrenergic blockade can cause theoretical hypertension because of unopposed α-adrenergic action.
9 sie 2022 · Beta antagonist receptors can reduce the reflex tachycardia associated with the use of phenoxybenzamine or other nonselective alpha blockers [3]. Recommendations advocate initiating treatment 7 to 14 days before surgery [3]. Selective alpha blockers, such as doxazosin, can be used in place of phenoxybenzamine [3].
9 cze 2011 · The α-adrenergic-receptor blockers and β-adrenergic-receptor blockers reduce the effects of catecholamines on end organs such as the brain, heart, gastrointestinal tract, and others.
