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Since the identification of B cells in 1965 (Cooper et al. 1965), three has been tremendous progress in our understanding of B cell development, maturation and function. A number of B cell subpopulations, including B-1, B-2 and regulatory B cells, have been identified.
26 sie 2024 · In newly published papers in Science and Cell, two research groups independently established pancancer landscapes of tumor-infiltrating B cells across major human cancer types by...
11 paź 2024 · B cells are a subtype of lymphocyte. They form part of the adaptive immune response and mediate humoral immunity. B cells can produce high-affinity antibodies and generate immunological memory.
In this study, we review B cell responses to acute viral infections, primarily influenza virus, from the earliest nonspecific B-1 cell to early, antigen-specific EF responses and finally to GC responses.
8 lip 2019 · A current model of B cell responses to antigens in the context of lymph nodes in vivo (as detailed in the text), showing a lymph node with a follicle and paracortical area (top right), then ...
Here, we provide a comprehensive roadmap of human B cell maturation with single-cell transcriptomics matched with bulk and single-cell antibody repertoires to define gene expression, antibody repertoires, and clonal sharing of B cell states at single-cell resolution, including memory B cell heterogeneity that reflects diverse functional and ...
31 sty 2022 · The contributions received for this Research Topic consisted of high-quality research papers and detailed overview papers that covered four main areas: (1) newly-identified B cell subsets, (2) mechanisms of B cell biology and pathology, (3) vaccination response and (4) B cell metabolism.
