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  1. According to a longitudinal study assessing autonomic symptoms in PD patients at the Hoehn–Yahr stage 1 with disease duration <2 years and following up those patients for three years, at least one symptom of autonomic dysfunctions was present in 71% of the PD patients in early stages and in all patients after 3-year follow-up .

  2. 24 gru 2020 · Symptoms of autonomic dysfunctions are frequently seen in PD patients, severely affecting the quality of life. This review summarizes the epidemiology, clinical manifestations, and treatment options of autonomic dysfunctions. The clinical significance of autonomic dysfunctions in PD early diagnosis and differential diagnosis is also discussed. 1.

  3. Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterised by motor dysfunction (parkinsonism) and several non-motor features. Dysautonomia is a significant non-motor feature as well as a neuropsychiatric symptom. Autonomic dysfunction can occur even in the early stages of PD, often preceding the onset of the classic

  4. Detection of autonomic dysfunction may therefore be helpful in diagnosing PD in the early or pre-motor stages, and/or in differentiating it from other parkinsonian disorders, such as multiple system atrophy and progressive supuranuclear palsy.

  5. 13 sie 2020 · Recognition of the role of nonmotor features in Parkinson’s disease (PD) has increased exponentially over the past 30 years, and autonomic dysfunction has emerged as an important aspect of nonmotor dysfunction, evident in both the early and later stages of PD.

  6. 19 mar 2021 · Therefore, early detection of autonomic dysfunction may allow an early diagnosis (Kaufmann et al., 2004, 2017) and seem to make an important contribution to the PD pathophysiology (Goldstein, 2014; Greene, 2014).

  7. 4 wrz 2023 · Autonomic symptoms (AS) are critical in Parkinson’s disease (PD). We aimed to determine the relative significance of clinical factors allowing predictions about incidence of AS, and examine AS...

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