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28 maj 2024 · Prognosis is favorable for low-grade tumors, with survival times approaching 7 to 8 years post-surgery. In anaplastic astrocytoma, therapy focuses on improving symptoms. Radiotherapy of partially resected tumors increases postoperative survival rates.
In our study, astrocytoma was diagnosed in young adults. The overall survival was 15 months, 9% (n=14) of patients presented a survival of 2 years, and 3% of patients survived 3 years. On average the number of years lost due to premature death and disability was 28.53 years.
15 paź 2021 · Background: Diffuse astrocytoma (DA) is a rare disease with inadequately understood epidemiological characteristics and prognosis. Identification of the factors associated with the survival in DA patients is therefore necessary.
Astrocytoma are the most common adult brain tumor, with Glioblastoma being the deadliest neuro-related malignancy. Despite advances in oncology, the prognosis for Astrocytoma, especially Glioblastoma, remains poor, and tracking disease progression is challenging due to a lack of robust biomarkers.
Conclusions: Patients diagnosed as WHO grade 4 according to the 5th edition WHO classification based on molecular alterations are more likely to have poorer prognosis. Therefore, treatment should be tailored to their individual needs. Further research is needed for the management of IDH-mutant astrocytoma is needed in the future.
CDKN2A homozygous deletion, PDGFRA amplification, and CDK4 amplification were found to be associated with shorter progression‐free survival (PFS) and overall survival (OS) in WHO grade II–III astrocytoma with IDH‐mutant. 3 Glioblastoma with IDH‐wildtype also had a worse prognosis than IDH‐mutant. 4 In the new edition of the ...
According to a meta-analysis of studies, the mean overall survival in patients with high-grade astrocytoma was 31.9 ± 2.7 months, for 2-year survival, 38.1% (95% CI: 27.5-50.1%) and for 5-year survival was 28.6% (95% CI: 24.1-33.4%).
