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  1. Large cross-sectional and prospective studies involving adults, adolescent children throughout the world showed a relationship between high body weight and asthma ... It has also been shown that atopy can be an important mediator of the link between obesity or obesity and asthma in this group of children. Studies underline the importance of ...

  2. 12 maj 2023 · Obesity has been associated with increased risk of adult asthma, however, not all studies have found a clear association between overweight and the incidence of asthma, and data on other...

  3. Identifying and understanding the mechanisms through which modifiable risk factors ameliorate or worsen the detrimental effects of obesity on asthma should lead to improved prevention and management of the “obese asthma phenotype” in children and adults.

  4. Obesity is associated with increased incidence of asthma that may be dose-dependent 2 and higher risk of severe asthma and asthma-related hospitalizations. 1,3 A study by Larsson and Burgess compiled more than 200,000 individuals from Mendelian randomization studies and de novo analyses of the FinnGenn consortium, concluding that higher BMI was ...

  5. 6 sty 2021 · Asthma and obesity are two epidemics affecting the developed world. The relationship between obesity and both asthma and severe asthma appears to be weight-dependent, causal, partly genetic, and probably bidirectional.

  6. 4 cze 2015 · Implications of obesity and the relationship with asthma. Obese asthmatics have multiple consequences related to excess adipose tissue, including mechanical or physiologic effects on lung function and the airways as well as changes in the immune response and metabolic effects.

  7. 1 sty 2024 · Obesity is associated with aggravation of the pathophysiology of asthma, including exacerbations, airway inflammation, decreased pulmonary function, and airway hyperresponsiveness. The present review addresses the characteristics of asthma with obesity, focusing especially on the heterogeneity caused by the degree of type 2 inflammation, sex ...

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