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This document is intended to support health care providers as they serve their patients with obesity and asthma. It includes summaries of data showing the connections between obesity and asthma, the impact of the environment, and potential mechanistic theories connecting the two.
21 lip 2020 · Asthma and obesity are two major chronic diseases in children and adolescents. Recent scientific evidence points out a causative role of obesity in asthma predisposition. However, studies assessing the real impact of excessive weight gain on lung function in children have shown heterogeneous results.
Obesity-associated asthma is a unique phenotype which tends to be more severe and resistant to conventional asthma treatments. Differences in respiratory mechanics, inflammation, comorbidities, the microbiome, and susceptibility to air pollution may be contributory factors.
4 cze 2015 · Understanding the link between obesity and asthma may have major public health implications and has the potential to lead to development of future therapies. This review will give a concise examination of the association between asthma and obesity and provide conclusions on the current body of literature.
5 paź 2023 · Abstract. Obesity is a common asthma comorbidity in adults, contributing to higher patient morbidity and mortality. Conversely, weight loss can reduce the impact of obesity on asthma and improve patient outcomes by diverse mechanisms including modulating airway inflammation, reducing oxidative stress, and improving lung function.
12 sie 2016 · Abstract. Obesity is a risk factor for asthma, and obese asthmatics have lower disease control and increased symptom severity. Several putative links have been proposed, including genetics, mechanical restriction of the chest and the intake of corticosteroids.
Obesity may impact currently available asthma biomarkers, and obesity-associated asthma specic biomarkers are needed. Whilst surgical weight loss interventions are associated with improvements in asthma control and quality of life, evidence for pragmatic conservative options are sparse.
