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  1. This state-of-the-art review article synthesizes evidence for existing and emerging treatment approaches for obesity-related asthma and highlights pathways that offer potential targets for novel therapeutics.

  2. This document is intended to support health care providers as they serve their patients with obesity and asthma. It includes summaries of data showing the connections between obesity and asthma, the impact of the environment, and potential mechanistic theories connecting the two.

  3. Obesity-associated asthma is a unique phenotype which tends to be more severe and resistant to conventional asthma treatments. Differences in respiratory mechanics, inflammation, comorbidities, the microbiome, and susceptibility to air pollution may be contributory factors.

  4. It has also been shown that atopy can be an important mediator of the link between obesity or obesity and asthma in this group of children. Studies underline the importance of establishing which obesity type/obesity index should be used in future studies of obesity and asthma, especially when determining phenotypes of asthmatic obesity (e.g ...

  5. 5 paź 2023 · The Breathe Easier through Weight Loss Lifestyle (BE WELL) study randomized 330 adults with obesity and with uncontrolled asthma to the Diabetes Prevention Program trial intervention versus standard of care. 11 Despite achieving the program’s lifestyle interventions in the treatment arm, a clinically significant improvement in the ACQ score ...

  6. 3 mar 2024 · diabetes and obesity as relevant to asthma • Establishing trust and reducing stigma with patients • Weight loss targets: ≥5% body weight, ideally ≥10% • Promoting active, interdisciplinary care Rates of obesity and (pre)diabetes are staggering and will impact severe asthma clinical care. Summary: Obesity, Diabetes and Severe Asthma

  7. 27 lut 2020 · The emerging evidence demonstrating the role of obesity and other lifestyle factors, such as diet and physical activity, on asthma outcomes warrants lifestyle interventions that can address...

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