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This state-of-the-art review article synthesizes evidence for existing and emerging treatment approaches for obesity-related asthma and highlights pathways that offer potential targets for novel therapeutics.
A comorbidity of specific interest is the metabolic syndrome. This syndrome identifies a cluster of metabolic diseases arising from systemic inflammation and insulin resistance, including pre-diabetes, diabetes, hypertension, and dyslipidemia.
5 paź 2023 · The Breathe Easier through Weight Loss Lifestyle (BE WELL) study randomized 330 adults with obesity and with uncontrolled asthma to the Diabetes Prevention Program trial intervention versus standard of care. 11 Despite achieving the program’s lifestyle interventions in the treatment arm, a clinically significant improvement in the ACQ score ...
1 maj 2020 · Evidence suggests that diets emphasizing the consumption of plant-based foods might protect against asthma development and improve asthma symptoms through their effects on systemic inflammation, oxidation, and microbial composition.
This document is intended to support health care providers as they serve their patients with obesity and asthma. It includes summaries of data showing the connections between obesity and asthma, the impact of the environment, and potential mechanistic theories connecting the two.
Obesity may impact currently available asthma biomarkers, and obesity-associated asthma specic biomarkers are needed. Whilst surgical weight loss interventions are associated with improvements in asthma control and quality of life, evidence for pragmatic conservative options are sparse.
Treatments directed against diabetes and cholesterol have been proposed for obesity-associated asthma, especially among those with underlying insulin resistance or dyslipidemia.
