Search results
22 mar 2017 · Cannabinoids, when co-administered with opioids, may enable reduced opioid doses without loss of analgesic efficacy (ie, an opioid-sparing effect). The aim of this study was to conduct a...
1 sty 2019 · Most DAU assays are competitive immunoassays (homogeneous or heterogeneous format) and are subjected to interferences from drug metabolites as well as other drugs with comparable structures to the analyte drug. These assays may be qualitative or quantitative. Alcohol testing employs enzyme assay.
27 mar 2020 · Here we addressed the role of metabolic processes in the course of the agonist medication-assisted treatment for opioid use disorder (OUD) with buprenorphine or methadone.
Activated opioid receptors are rapidly desensitized by the action of GPCR-regulated kinases (GRKs), which phosphorylate receptors, and β-arrestins, which internalize phosphorylated receptors. The interaction dynamics of opioid receptors with these proteins, and numerous other intracellular partners, gives rise to varied signaling outcomes.
22 kwi 2022 · Cannabinoid co-administration may enable reduced opioid doses for analgesia. This updated systematic review on the opioid-sparing effects of cannabinoids considered preclinical and clinical...
All cases presented participants with one of three commonly prescribed medication classes (opioids, CNS depressants, or antibiotics) in addition to common substances (over the counter medications (OTCs), supplements, food, alcohol, or other prescription medications) that may cause one or more DDIs.
1 cze 2023 · Opioids are a mainstay in acute pain management and produce their effects and side effects (e.g., tolerance, opioid-use disorder and immune suppression) by interaction with opioid receptors. I will discuss opioid pharmacology in some controversial areas of enquiry of anaesthetic relevance.
